Learn about acute renal failure , a sudden loss of kidney function that requires prompt diagnosis and treatment. Find out the common causes, symptoms, complications, and treatment options for this serious condition. Acute kidney injury (AKI) is a clinical syndrome manifested by a rapid or abrupt decline in kidney function and subsequent dysregulation of the body electrolytes and volume, and abnormal retention of nitrogenous waste. AKI was formerly known as acute renal failure . AKI is a complex condition with a wide range of causes, including ischemic injury and exposure to nephrotoxic agents. [1] The widely accepted Kidney Disease : Improving Global Outcome (KDIGO) definition of AKI is based on the ... AKI is a term for when kidneys suddenly lose their ability to filter waste from the blood. It replaces the term ' acute renal failure ' and can have many causes, symptoms, and complications. Introduction Acute renal failure , also known as acute kidney injury (AKI), is a sudden and rapid decline in kidney function. It is a potentially life-threatening condition that can have various causes and can lead to serious complications if not managed promptly. In this article, we will explore the etiopathogenesis, or the underlying mechanisms, of acute renal failure , and discuss the pharmacotherapy options available for its treatment.