Discover everything you need to know about azelaic acid —what it is, how it works, 15 science-backed benefits, 10 potential side effects, usage tips, precautions, and who should or shouldn’t use it for healthier, clearer skin. Azelaic acid is a dicarboxylic acid compound that is derived from a type of yeast that is present on healthy skin, and is also found in wheat, rye and barley. A synthetic form is used in skin care products. Azelaic acid (AzA), a saturated dicarboxylic acid, is indicated for the treatment of acne vulgaris, rosacea, melasma, and post-inflammatory hyperpigmentation. Azelaic acid , a naturally occurring dicarboxylic acid derived from grains such as wheat, barley, and rye, has garnered significant attention in dermatology and cosmetic science for its multifaceted bioactivity. This article explores the molecular and cellular mechanisms, the clinical evidence supporting its efficacy, its regulatory status, and formulation considerations relevant to its use in cosmetics and therapeutic skincare products.
