Buerger disease decreases blood flow to the hands and feet. As the disease gets worse, the skin and tissue in the affected areas do not get enough blood. This can cause painful open sores that do not heal. Buerger’s disease is a serious condition that affects blood vessels in the arms and legs, causing pain, tissue damage, and sometimes amputation. It is strongly linked to tobacco use and has no cure, only prevention by quitting smoking. Thromboangiitis obliterans (TAO), an inflammatory vasculopathy also known as Buerger disease, is characterized by an inflammatory endarteritis that causes a prothrombotic state and subsequent vaso-occlusive phenomena. The inflammatory process is initiated within the tunica intima. Thromboangiitis obliterans, also known as Buerger disease, is a smoking-related inflammation and clotting of blood vessels in the hands and feet. Learn about its signs, symptoms, diagnosis, prevention and treatment options.

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