What is Canine Distemper (CD)? Canine Distemper (CD) is a deadly viral infection in dogs caused by the Canine Distemper Virus (CDV), now known as Canine morbillivirus. It is a highly contagious disease that attacks multiple organs and organ systems of the infected dog. Canine distemper is a highly infectious, systemic, viral disease of dogs that occurs worldwide. Dogs commonly exhibit systemic clinical signs (fever, lethargy, loss of appetite), respiratory signs (nasal discharge, pneumonia), and GI signs (diarrhea), variably followed by neurologic signs (muscle twitching, focal or generalized seizures), which may be delayed. Vaccination is available and is generally effective. Diagnosis is made by recognition of the clinical signs, along with confirmation ... Canine distemper is a viral disease that affects many mammal species, including dogs, wolves, and ferrets. It causes fever, respiratory and gastrointestinal problems, and can lead to neurological symptoms and death. Learn about its history, symptoms, transmission, and prevention. Learn about canine distemper, a highly contagious viral disease of dogs and other animals that can cause fever, respiratory, GI, and neurologic signs. Find out how to diagnose, treat, and prevent canine distemper with vaccination and antibody tests.