Learn about the femur , the longest and strongest bone in the human body, that supports weight and enables locomotion. Find out its location, structure, articulations, vascular supply, and clinical significance. Learn about the femur , the longest and strongest bone in the body, that connects the hip and knee joints. Find out its landmarks, mechanics, blood supply, muscle attachments and common disorders. The femur is the only bone in the thigh and the longest bone in the body. It acts as the site of origin and attachment of many muscles and ligaments, and can be divided into three parts; proximal, shaft and distal.