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What is Fournier’s Gangrene? Fournier’s gangrene is a fast progressing, tissue-destroying infection on the genitals and nearby region. It is a medical emergency that can be fatal without immediate treatment. The infection-causing organisms can enter the genitalia, perineum, or colorectal area through a wound. Fournier gangrene is necrotizing fasciitis of the perineum. It is a true urological emergency due to the high mortality rate but fortunately, the condition is rare. It is primarily a clinical diagnosis and definitive treatment, typically consisting of surgical debridement and antibiotics. Fournier's gangrene: Gangrene can be a troublesome disease, but Fournier's gangrene is particularly worrisome. This type of gangrene attacks your genitals. Learn more. Fournier gangrene was first identified in 1883, when the French venereologist Jean Alfred Fournier described a series in which 5 previously healthy young men suffered from a rapidly progressive gangrene of the penis and scrotum without apparent cause. This condition, which came to be known as Fournier gangrene, is defined as a polymicrobial n...