What are the side effects of Glycomet 500 SR Tablet? Side effects of Glycomet 500 SR Tablet include diarrhoea, flatulence (gas), headache, fatigue, heartburn, nausea, constipation and a metallic taste in the mouth. Glycomet 500 SR Tablet 20'S is used to manage Diabetes. Find Glycomet 500 SR Tablet 20'S uses, substitutes, side effects, composition, directions for use, drug interactions, precautions and buy online at best price. Glycomet 500 SR Tablet is used to manage blood sugar levels in people with type 2 diabetes. It contains metformin, which helps control blood sugar by reducing glucose absorption and production in the liver. It is also prescribed to treat polycystic ovary syndrome (PCOS).