Lymphocytosis refers to an increased number of lymphocytes in the bloodstream. Lymphocytes are a type of white blood cell that plays an important role in the immune system and helps in fighting off bacterial and viral infections. In lymphocytosis , high lymphocyte count in the blood may be suggestive of an evolving infection, an underlying systemic disorder (e.g., leukemia, lymphoma), or an iatrogenic cause (e.g., medication-induced hypersensitivity reactions). Lymphocytes are white blood cells that help fight infections and diseases. Learn about the different types of lymphocytes, what they do, and what high or low levels mean for your health. The higher count usually comes after an illness. It is most often harmless and doesn't last long. But the higher count might be the result of something more serious, such as a blood cancer or a chronic infection. More tests can show if the lymphocyte count is a cause for worry. Lymphocytosis (High Lymphocyte Count) is an increase in white blood cells called lymphocytes. Know about its causes, symptoms and treatment.