Neosporin Ointment is a combination medicine which works by stopping the growth of infection-causing bacteria on your skin. It prevents the synthesis of essential proteins necessary for the survival of bacteria. Overview: Topical triple antibiotic is applied to your skin to reduce the risk of infection from minor wounds or injuries. Topical triple antibiotic should only be used on your skin after... Neosporin Antibiotic Ointment is a good over-the-counter antibiotic for minor skin wounds, as it combines three effective antibiotics (Bacitracin, Neomycin, and Polymyxin B) to help prevent or treat bacterial infections. Neosporin ointment is a versatile and effective solution for preventing infections and promoting healing in minor cuts, scrapes, and burns . Its triple antibiotic composition ensures broad-spectrum antibacterial action, making it a valuable addition to any first aid kit.