Nuance is a subtle difference in sound, feeling, appearance, or meaning . Learn how to use this word in sentences, synonyms, pronunciation, and translations. NUANCED definition : 1. made slightly different in appearance, meaning , sound, etc.: 2. made slightly different in…. Learn more. Unlock the secrets of " nuance "! Explore the etymology, real-world examples, and even famous quotes that capture the essence of this joyful word. Nuance definition : A subtle or slight degree of difference, as in meaning , feeling, or tone; a gradation.