Learn about common skin lesions , such as moles, warts, freckles, and acne, and how to prevent or treat them. See pictures and descriptions of different types of skin lesions and when to see a doctor. A skin lesion is an abnormal growth or rash on the skin as compared to normal skin . There are two main categories of skin lesions : primary and secondary lesions . Primary skin lesions are abnormal skin conditions that may be present at birth or acquired later. Secondary skin lesions are a result of irritated or manipulated primary skin lesions . Skin lesions can range in size, color, and shape. From small bumps to large patches of discoloration, some are harmful, and some are benign.