Generic Name Sulfasalazine DrugBank Accession Number DB00795 Background Sulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). 16, 10 Metabolized by intestinal bacteria, sulfasalazine is broken down into mesalazine and sulfapyridine, 2 compounds that carry out the main pharmacological activity of sulfasalazine ... Description Sulfasalazine is used to treat and prevent acute attacks of mild to moderate ulcerative colitis. It works inside the bowels by helping to reduce the inflammation and other symptoms of the disease. Sulfasalazine enteric-coated tablets are used to treat adults and children with rheumatoid arthritis in patients who have not been helped by or who cannot tolerate other medicines (eg, salicylates or NSAIDs) for rheumatoid arthritis. This medicine is available only with your doctor's ... Sulfasalazine is a prescription drug that treats ulcerative colitis, rheumatoid arthritis, and juvenile rheumatoid arthritis. It works by lowering inflammation and reducing pain and swelling, but it may cause serious side effects such as liver, kidney, or blood toxicity, low sperm count, and allergic reactions. Sulfasalazine is a sulfonamide drug used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It is broken down by intestinal bacteria into sulfapyridine and mesalazine, which have anti-inflammatory effects in the colon.
