Use vs Uses - What's the difference? Uses is a anagram of use. As nouns the difference between use and uses is that use is the act of using while uses is plural of lang=en. As verbs the difference between use and uses is that use is to accustom; to habituate while uses is third-person singular of use. Guide to Uses of Excel. Here we discuss the top 13 important uses of Excel that includes Online Access,Goal Seek Analysis,Data Filtering, etc with examples. Synonyms for USES : utilizes, applies, employs, exploits, operates, harnesses, exercises, draws upon; Antonyms of USES : ignores, neglects, misuses, misapplies, disuses, nonuses, dislikes, hatreds Learn the meaning, usage, and origin of the word "use" and its related terms. Find out how to use "use" in different contexts, such as law, philosophy, and idioms.