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Ageing is the process during which structural and functional changes accumulate in an organism as a result of the passage of time. The changes manifest as a decline from the organism’s peak ... In 1991, the book Evolutionary Biology of Aging offered the following definition of aging: a persistent decline in the age-specific fitness components of an organism due to internal physiological deterioration (Rose, 1991). This definition has since been used by others a number of times. However, it was only a modest generalization of a definition proffered by Alex Comfort over three editions (1956–1979) of his key book The Biology of Senescence (Comfort, 1979): “a progressive increase ... AGING definition: 1. US spelling of ageing 2. relating to getting older: 3. used to describe a person or thing that…. Learn more. You know that aging likely will cause wrinkles and gray hair. But do you know how getting older will affect your teeth, heart and sexuality? Find out what changes to expect as you age — and how to boost your chances of good health at any age. It's common for arteries to become stiffer over time.