Amyloidosis is a rare disease. Immunoglobulin light chain (AL) amyloidosis (also called primary systemic amyloidosis ) is the most common type of amyloidosis . Amyloidosis occurs when amyloid proteins are deposited in tissue and organs. It may have a primary cause, may be inherited, or may be secon... Amyloidosis is a buildup of abnormal proteins in your tissues and organs. Explore the symptoms and treatments of this rare but serious disease. Overview Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a protein called amyloid builds up in organs. This amyloid buildup can affect the way organs work. Amyloidosis may affect the heart, kidneys, liver, spleen, nervous system, soft tissue, muscle and digestive tract. Learn about Amyloidosis , including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find resources and
