Get a quick, free translation! APPENDIX definition : 1. a small tube-shaped part that is joined to the intestines on the right side of the body and has…. Learn more. A small saclike organ located at the upper end of the large intestine . The appendix has no known function in present-day humans, but it may have played a role in the digestive system in humans of earlier times. The appendix is also called the vermiform appendix because of its wormlike (“vermiform”) shape. Definition of appendix noun in Oxford Advanced Learner's Dictionary. Meaning , pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.