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ESR test measures the rate of red blood cells settling in a blood sample. It can indicate inflammation in the body, but not a specific disease. Learn about the normal range, causes of high or low ESR, and possible complications of the test. Learn which conditions your sedimentation rate helps your doctor diagnose. Also, find out how the test can guide your treatment. ESR test detects inflammation. Learn normal ESR ranges by age and gender, influencing factors, and what abnormal levels might signal for effective diagnosis. Erythrocytes are red blood cells. The sedimentation rate is the time it takes for your red blood cells to settle at the bottom of a test tube. An erythrocyte sedimentation rate (ESR) is a blood test that can show if you have inflammation in your body.