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malignant Medspeak adjective Tending to harm, kill, maim; pernicious, life-threatening; resistant to treatment; severe (as in malignant hypertension); threatening to life; virulent. Oncology adjective Referring to invasion and destruction of nearby tissue and spread to regions; referring to a neoplasm that invades surrounding tissue—which generally is unencapsulated—and grows by invasion, with vascular and lymphatic metastases. “ Malignant ” is a term used to describe active cancer cells or tumors. This is a general term, however, and may be applied to any condition that is serious enough to lead to a person’s death. The meaning of MALIGNANT is tending to produce death or deterioration; especially : tending to infiltrate, metastasize, and terminate fatally. How to use malignant in a sentence.
