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Medscape - Myasthenia Gravis, neuromuscular blocker reversal dosing for Bloxiverz (neostigmine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Point of Care - Clinical decision support for Neostigmine. Treatment and management. Indications, Mechanism of Action, Administration, Adverse Effects, Contraindications, Monitoring, Toxicity, Enhancing Healthcare Team Outcomes Neostigmine is a cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants such as gallamine and tubocurarine. Neostigmine, unlike physostigmine, does not cross the blood-brain barrier. The drug information on NEOSTIGMINE include structure, IUPAC, physiochemical properties, synthesis, SAR, MOA, therapeutic uses, side effects and MCQs for GPAT and other exam preparations.