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Non-HDL cholesterol is essentially the total of all the “bad” cholesterols in your blood. It includes low-density lipoprotein (LDL), very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein (a) – all the particles that can contribute to plaque buildup in arteries. Understand safe levels of non-HDL cholesterol and why it's vital for your heart health. This article looks at what non-HDL cholesterol means, what cholesterol levels fall within the healthy range, and how to lower cholesterol levels that are too high. Non-HDL cholesterol refers to all your cholesterol values minus your HDL cholesterol . In essence, it is a measure of the not-so-good cholesterol levels in your body. The higher your non-HDL levels, the greater your risk of cardiovascular disease.