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Periorbital edema refers to swelling around the eyes that causes them to appear puffy . Learn about symptoms, diagnosis, outlook, and more. Puffy Eyes : Causes, Symptoms, & Treatment Options Puffy eyes refer to the swelling or puffiness around the eyes , often accompanied by dark circles. This common condition affects people of all ages and can make one appear tired, stressed, or older than they are. Puffiness around the eyes can result from temporary issues like crying, lack of sleep, or more persistent causes such as allergies or underlying health problems. While eye puffiness (periorbital edema) is often due to a lack of sleep or allergy, it may also indicate a serious medical issue like thyroid disease or diabetes. In most cases, puffy eyes are only a cosmetic issue and not a sign of a more serious problem. Here’s how you can get rid of puffy eyes .