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Sucralfate is used to treat and prevent duodenal ulcers and other conditions as determined by your doctor. It works by forming a barrier or coat over the ulcer. Sucral Suspension is used in the treatment of ulcers in the stomach and intestine. It contains the active ingredient sucralfate which promotes the healing of ulcers by forming a coating over them which acts as a physical barrier. Sucral Suspension is taken one hour before meals preferably at bedtime in the dose and duration advised by the doctor. Sucralfate , sold under various brand names, is a medication used to treat stomach ulcers, gastroesophageal reflux disease (GERD), radiation proctitis, and stomach inflammation and to prevent stress ulcers. [3][4][5] Its usefulness in people infected by H. pylori is limited. [3] What is sucralfate? Sucralfate is used short-term (up to 8 weeks) to treat an active duodenal ulcer . Sucralfate works mainly in the lining of the stomach and is not highly absorbed into the body. sucralfate adheres to ulcer sites and protects them from acids, enzymes, and bile salts.