Terms of the offer
COAGULATION definition: 1. the process by which blood changes into a solid state to form a solid seal 2. the process by…. Learn more. Blood Coagulation Blood coagulation or clotting is an important phenomenon to prevent excess loss of blood in case of injury or trauma. The blood stops flowing from a wound in case of injury. The blood clot or ‘coagulum’ is formed by a network of fibrin threads. In this network, deformed and dead formed elements (erythrocytes, leukocytes and platelets) get trapped. The coagulation proteins are the core components of the coagulation system that lead to a complex interplay of reactions resulting in the conversion of soluble fibrinogen to insoluble fibrin strands. Key Points The coagulation cascade is a series of reactions, which is classically divided into three pathways: the contact (also known as the intrinsic) pathway, the tissue factor (also known as the extrinsic pathway), and the common pathway. The intrinsic pathway occurs when negatively charged molecule contact causes a cascade of factors that produce factor X. The extrinsic pathway occurs when tissue damage causes the release of tissue factor, creating a smaller cascade that produces factor ...
