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Evidence suggests that the CXXC type zinc finger (ZF- CXXC ) protein 5 (CXXC5) is a critical regulator/integrator of various signaling pathways that include the estrogen (E2)-estrogen receptor α ... CXXX Roman Numerals are written as numbers by combining the converted roman numerals. Here we will explain how to convert CXXX in the correct Arabic number translation. The CXXC domain, first identified as the reader of unmodified CpG dinucleotide, plays important roles in epigenetic regulation by targeting various activities to CpG islands. Here we systematically measured and compared the DNA-binding selectivities of all known human CXXC domains by different bindi … CXXC1 is a protein that binds to CpG sequences and regulates gene expression. It is also known as CGBP, CFP1, PHF18, SPP1, ZCGPC1, hCGBP, PCCX1 and has orthologs in human and mouse.